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Vaccine Supply Update

06 March 2018

The following is an update provided by Public Health Englandon the supply situation for vaccines purchased direct from the manufacturers (e.g. for travel and risk groups):

Diphtheria, Tetanus and Poliomyelitis (inactivated) Vaccine

Sanofi Pasteur: Limited supplies of Revaxis are available. There are likely to be order restrictions in place for travellers. Please contact Sanofi Pasteur for information regarding availability. Sanofi Pasteur Tel: 0148 350 5515.

Hepatitis B

To ensure vaccine availability for those at highest and most immediate risk of exposure to hepatitis B, all hepatitis B containing monovalent and bivalent (HepA/HepB) vaccines are currently under supply management processes, detailed guidance is available here

In Scotland a mechanism is in place to allow for exceptional orders if there is an urgent and immediate need for an individual following a thorough risk assessment, this is through the local NHS Board Vaccine Holding Centre

Hep B Adult:

  • GSK: Engerix B PFS singles are available.
  • GSK: Engerix B PFS packs of 10 are available.
  • GSK: Very limited supplies of Engerix B vials are available.
  • GSK: Fendrix is available.
  • MSD: Limited supplies of HBVAXPRO 10μg are available. Supplies are expected to be restricted throughout 2018.
  • MSD: Limited supplies of HBVAXPRO 40μg are available. Supplies are expected to be restricted throughout 2018.

Hep B Paediatric:

  • GSK: Engerix B Paediatric singles are available.
  • MSD: Limited supplies of HBVAXPRO 5μg are available. Supplies are expected to be restricted throughout 2018.

Hepatitis A Vaccine

Hep A Adult:

  • GSK: Supplies of Havrix PFS singles, PFS packs of 10 and vials in singles are available. However, there may not be sufficient stock in each presentation to accommodate demand.
  • Sanofi Pasteur: Limited supplies of Avaxim are available. It is likely that there will be order restrictions in place.
  • MSD: VAQTA is currently unavailable and there will be intermittent supplies of during 2018.

Hepatitis A Paediatric:

  • GSK: Havrix Paediatric singles and packs of 10 will experience supply constraints until spring 2018.
  • MSD: VAQTA Paediatric is currently available with supplies expected throughout 2018.

Combined Hepatitis A and B

  • GSK: Twinrix Adult and Paediatric presentations are available.
  • GSK: Ambirix is available.

Combined Hepatitis A and Typhoid

  • GSK: GSK is discontinuing Hepatyrix vaccine that has been under constrained supply for several years due to challenges associated with its manufacturing.
  • Sanofi Pasteur: Viatim is currently available.

Typhoid

  • GSK: GSK is discontinuing Typherix vaccine that has been under constrained supply for several years due to challenges associated with its manufacturing.
  • Sanofi Pasteur: Typhim is available to order without restrictions.
  • PaxVax: Vivotif is available.

Rabies

  • GSK: limited supplies of Rabipur are available. Supply is being prioritised to hospitals and GPs for use in notified post exposure cases only.
  • Sanofi Pasteur: Limited supplies of Rabies BP are available. It is likely that there will be order restrictions in place.

Contact Details:

GSK Tel: 0208 047 5000

GSK Supply Portal: https://hcp.gsk.co.uk/supply.html

Sanofi Pasteur Tel: 0148 350 5515

Sanofi Supply Portal: https://www.sanofipasteur-portal.co.uk/supply.php

MSD Tel: 0199 245 2094

PaxVax Tel: 0152 521 7516